Loceryl Nail Lacquer Clinically Proven for the Treatment of Onychomycosis
  • Highly effective and safe topical treatment for fungal nail infections1, 2, 3, 4
  • Only needs to be used once a week
  • Loceryl Nail Lacquer contains the active ingredient, 5% amorolfine, has been clinically proven to treat fungal nail infections1, 2, 3, 4
  • Recommended by dermatologists
  • World-wide No. 1 topical dermatological antifungals for onychomycosis5
1. Med Mycol. 2009 Nov; 47(7): 753-8
2. JEADV 2005; 19(Suppl 1): 25-33
3. J Dermatol Treat 2005; 16: 299-307
4. Data on file
5. IMS WW MAT Jun-2011 Topical dermatological antifungals for onychomycosis
Product Information
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What is onychomycosis and what causes it?

Onychomycosis is an infection of fingernails and/or toenails caused by a small micro-organism called a fungus. There are different species of fungi, such as dermatophytes, yeasts and moulds. The fungus settles under the nail and once installed in the nail bed begins to multiply. The fungus is difficult to reach as the nail itself protects it.

Onychomycosis is more common in toenails. Socks and shoes keep your toenails warm and moist, a perfect environment for the fungus to grow. Foot injuries and tight, uncomfortable shoes increase the possibility of contracting onychomycosis. This infection is not necessarily linked to hygiene problems.

What are the symptoms of onychomycosis?
    Your nail may:
  • Change colour – white, yellow, brown
  • Become flaky
  • Thicken
  • Become painful
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These symptoms may worsen overtime if left untreated:
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What are the treatment choices for nail fungal infections?

Before starting any treatment against onychomycosis, you should seek the advice from a dermatologist to confirm the diagnosis and obtain a prescription for an effective treatment for you. Onychomycosis may be treated with antifungal drugs that kill the fungi and prevent their embedded spores to grow and multiply. There are topical and oral treatments (prescription only) available:

Topical Treatment
(Loceryl Nail Lacquer)
  Indications   For mild to moderate or/and non-matrix involved onychomycosis   For moderate to severe or/and matrix-involved onychomycosis, and in combination with a topical treatment is recommended.  
  Dosage and timeline   Once weekly application on the infected nail(s) until the infected section of the nail has grown sufficiently to be completely cut off.   Usually once or twice a day for several months, or as directly by physicians, until cure is achieved  
  Benefits   As these antifungals are not conveyed by the bloodstream, they are not likely to provoke systemic/general side effects as opposed to oral antifungals. They can be used as long as needed for the infected section of the nail to grow and be cut off.   The drug reaches the site of infection (the nail bed) via the blood stream. To be effective, these drugs need to accumulate in the nail bed in sufficient quantity. This requires several weeks.  
  Cautions   May cause irritations if apply to wounds   These treatment can cause some serious side effects, such as liver toxicity.  
How can I prevent onychomycosis?
  • Keep your feet clean and dry. Make sure you dry between the toes.
  • Use socks made of natural materials (cotton or wool) to permit air circulation.
  • Change your socks daily.
  • Do not walk on bare feet in public pools, showers, changing rooms etc.
  • Make sure you use sterilized tools for manicure/pedicure at home or salons.

Anyone can contract onychomycosis. However, there are several people at higher risk than others:
- Elderly
- Those who use public pools, bathrooms, changing rooms etc.
- Those who have had athlete's foot (a common fungal infection of the feet)
- Those who regularly receive manicures or pedicures
- Those with medical problems such as trauma, diabetes, bone and joint diseases, obesity, foot trauma during sports and vascular or immunodeficiency.

Onychomycosis is difficult to transmit from person to person. In order to be contagious these micro-organisms require a warm or humid medium, such as those found in shower stalls, pools and areas in manicure salons. The fungus can be passed along on a nail file, a hand/foot bath or a pool deck. Over time, onychomycosis can also spread from one nail to another.

Treatment length varies depending on what type of infection you have, whether it affects your finger or toenails, how many nails are affected etc. Even after the fungus and spores have been killed (mycological cure), it will take about 6 months for fingernails and 12 months for toenails to be normal in appearance. This is the time needed for your nails to grow out.

Cure for onychomycosis is only achieved when both the fungi and their spores are eliminated. Fungi are usually killed within weeks. Spores are much more resistant and can survive several months embedded in the formerly infected section of the nail. This is why a nail can be considered cured only when the formerly infected section of the nail has grown out and is cut off. This can take several months depends on the location of the infection.

Nails often get re-infected because although the fungus has been killed, the spores survive within the remaining affected nails. For this reason, one has to wait until the nail grows out and the affected nail portion can be cut off, before stopping treatment.

In addition to taking care of your nails as outlined previously, the nail lacquer can be used until such time as you are able to cut the entire affected portion of the nail. Nail lacquer is indicated for long-term use as it is safe.